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Is Tramadol more potent than Codeine? (Tramadol and Codeine)



Tramadol Oral Tablets is a prescription drug available as sustained or extended-release (ER) and immediate-release tablets. Tramadol is also known as a sustained-release oral capsule. Immediate release medicine or drug is released instantly in the body. Sustained or Extended-release (ER) drugs are slowly released into the body over time.

Both tramadol oral capsules are also obtainable as generics. Immediate-release tablets are also available under the brand name medicine Ultram. Generic medications are usually cheaper than branded versions. They may not be available in all strengths or forms as branded medicines in a few cases. Tramadol is a regulated substance.

It means that it should only be used under the strict or close supervision of a pharmacist or a doctor.


Codeine relates to a class of medicines called narcotic (narcotic) analgesics and a class of medications called antitussives. When codeine is used to treat pain, it acts by changing the way the brain & nervous system answer or respond to pain.

Uses of Tramadol and codeine

Tramadol uses

Tramadol medicines are mainly used to treat moderate to serious or severe pain. Tramadol can be used as a part of combination therapy. It means you can need to take it with other medicines.

Uses of Codeine

Codeine is used to alleviate moderate to slight aches. It relates to the group of medications known as pain medications (narcotic analgesics). This medication works on the CNS (central nervous system) to relieve pain.

Is Tramadol stronger or more potent than codeine?

Both tramadol and codeine are prescription opioid analgesics and appear to be equally effective in analgesia. Tramadol and codeine are both generally prescribed to treat moderate pain. In addition to relieving pain, codeine is also used as a cough suppressant. Both medicines can be combined with other ingredients such as paracetamol or acetaminophen.

Tramadol and codeine are weaker than other medicines in this class, such as morphine. Codeine, like many other narcotics, is derived from poppy plants, but tramadol is artificially manufactured.

Side effects of tramadol and codeine may include: 

  • Confusion
  • Potential for addiction
  • Constipation
  • Sedation
  • Dizziness

Although these two medications are weaker than other opioids, tramadol and codeine are still addictive and may cause severe withdrawal symptoms if abruptly discontinued.

There are a few differences between the two medications’ side effects profiles:

Tramadol can pose a slightly decreased risk for addiction than codeine medicine. Although tramadol is associated with a lower risk of respiratory depression and constipation than codeine, it can improve the chance for serotonin toxicity when mixed or combined with other medications that increase the brain’s serotine chemical. Symptoms of serotonin toxicity include tremors, sweating, and headaches.

People with a history of seizures cannot take tramadol to relieve pain because of the potential risk of attacks. For this exact reason, tramadol cannot be taken with a class of older antidepressants known as MAOIs (monoamine oxidase inhibitors).

How should I take Tramadol?

Take tramadol exactly as your pharmacist doctor told or prescribed you. Follow all of the instructions on the prescription label to read all dosing guidelines. Do not use tramadol in large quantities or longer than the specified time. Talk to your pharmacist if you feel an increasing or a growing urge to take this drug.

Do not share tramadol with others, especially those with a history of drug addiction. Abuse may cause addiction, overdose, or death. Always keep your medicine out of the reach of others. It is illegal to sell or transfer this medicine without any license.

Always buy tramadol online from an authentic site with enough experience and knowledge about its usage. If you purchase it from any irrelevant place, it may harm you.


Tramadol medicine can be taken with food or on an empty stomach, but always take it the exact way each time.

Swallow whole tablets or capsules to avoid potentially fatal overdose. Do not crush, chew, break, open, or melt (dissolve).

Do not crush or break the tramadol tablets to inhale the powder or mix it with the liquid and inject the drug intravenously. This practice brought death. If you suddenly stop using tramadol, you may experience withdrawal symptoms. Talk to your pharmacist or doctor before stopping the drug.

Store at room temperature away from heat and moisture. Always track your medicine. You need to be careful if someone is misusing it or without any prescription. Do not store the remaining tramadol. A single dose can kill someone who has accidentally or improperly used it.

Consult or ask your pharmacist for the location of your drug recovery and disposal program. If there is no collection program, place the remaining medicine in a sealed plastic bag, mix it with Kitty’s toilet or coffee grounds, and throw it in the trash.

How should I take Codeine?

Codeine generally comes as a capsule, tablets, and a liquid (solution) to take from the mouth. It is generally taken each 4-6 hours as required.

Follow the guidelines and instructions on your prescription carefully, and ask your pharmacist or doctor to explain any part you are not understanding. Take this medicine the same as directed.

If you have been taking codeine for more than a few weeks, do not stop taking the drug without consulting your doctor.

Your doctor may gradually reduce your dose. Sudden withdrawal of codeine causes restlessness, dilated pupils (the black circle in the center of the eye), watery eyes, irritation, anxiety, nasal discharge, difficulty falling asleep or staying asleep, nausea, sweating, rapid, you can experience withdrawal symptoms such as fast heartbeat, widened pupils, fast heartbeat, teary eyes, hair standing on your arms, nausea, loss of appetite, vomiting, diarrhea, stomach cramps, muscle or back pain.

Shake the mixture or solution well before using the medication. It would be best not to use the household spoon to measure the dose. Always use a measuring spoon or cup that comes with the drug or use a particular type of measuring medication spoon only.

Conclusion- Both medicines are equally effective. If you take them carefully, under the prescription of your pharmacist, it would be best for you. Always buy medication from an authentic place. If you use Codeine and Tramadol without any knowledge, it won’t give you any positive results. If you are looking for a place or a store where you may get correct information about its usage, you may buy Tramadol and Codeine from our store. We provide a 10% discount on all medications.

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